Obesity Research Updates

For Medical Professionals

Bariatric surgery was linked to positive outcomes in pregnancy, such a reduced risk for gestational diabetes and excessive fetal growth, according to data from a population-based study. However, this study was also associated with negative outcomes, including an increased risk for small-for-gestational age infants and possibly increased mortality. These findings suggest the need for increased monitoring during pregnancy.
Approximately one-quarter to one-third of all children who have obesity and enter weight management programs are depressed, according to 2 studies.
VBLOC vagal blocking therapy delivered via the Maestro System is now approved to treat adults age 18 to 65 years with a body mass index (BMI) of 40 to 45 kg/m2 or >35 kg/m2 and 1 or more obesity-related complications.
Saxenda (liraglutide [rDNA origin] injection) is now approved for chronic weight management in addition to a reduced-calorie diet and physical activity in adults with a body mass index (BMI) of .....
The U.S. Food and Drug Administration (FDA) expanded the approved uses of Vyvanse® (lisdexamfetamine dimesylate) to include treatment of moderate-to-severe binge-eating disorder in adults, making it the first medication approved to treat this condition.
Weight loss from bariatric surgery appears to reverse the increased cerebral metabolism and poor executive function associated with obesity, according to a study reported in the August 26 Journal of Clinical Endocrinology and Metabolism.
Members of the Endocrinologic and Metabolic Drugs Advisory Committee of the U.S. Food and Drug Administration (FDA) voted 14-1 in favor of approving the once-daily human GLP-1 analogue liraglutide for the treatment of obesity.
The U.S. Food and Drug Administration (FDA) has approved the combination agent naltrexone/bupropion (Contrave) extended release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults who are obese (BMI ≥ 30 kg/m2) or overweight (27 kg/m2) and have at least one weight-related comorbidity, including hyperension, type 2 diabetes, and dyslipidemia.
The concept of offering bariatric surgery at a BMI lower than 35 has emerged as a viable option for individuals at high risk. As emerging data on safety and long-term efficacy emerges for bariatric surgery in this patient population.
A review of bariatric surgery studies published between 2003 and 2012—the most recent review of its kind—confirms that bariatric surgery provides “substantial and sustained effects on weight loss and ameliorates obesity-attributable comorbidities in the majority of bariatric patients.
Bariatric surgery is increasingly being used to treat adolescents with severe obesity, despite limited data regarding the safety of these procedures in this age group. Now, the largest study on this topic shows that most teenagers that underwent bariatric surgery for weight loss had few short-term complications, as reported in "JAMA Pediatrics."
The AACE currently does not endorse the new cholesterol and obesity guidelines from the American Heart Association (AHA)/American College of Cardiology (ACC), according to an AACE press statement.
An obesity algorithm released by the American Society of Bariatric Physicians (ASBP) is designed to help navigate a physician's role in medically treating and caring for patients affected by obesity.
Overweight diabetic patients who undergo gastric bypass surgery reduced their 10-year risk of having a heart attack by 40% and their risk for suffering a stroke by 42%.
Diabetes poses the highest risk for mortality from obesity, and should be considered when deciding who should have bariatric weight-loss surgery
AACE, ACE, and TOS published clinical practice guidelines to teach healthy eating in order to prevent and manage endocrine and metabolic disorders.

Bariatric surgery was found to be more effective than nonsurgical interventions at controlling blood glucose for patients with diabetes at the low end of the obesity spectrum (body mass index [BMI]

In mild to moderately obese patients with diabetes, the use of bariatric surgery is more likely to meet established diabetes goals in the short-term than lifestyle-medical management alone, but wit

Prejudice or bias against overweight people can influence decisions about diagnosis and treatment.
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